Do not pick at the infected skin or try to treat it yourself. Be sure to cover the area with a bandage. Wash your hands with soap before and after bandaging the wound. The MRSA infection is spread through contact with an infected person. This could be skin-to-skin contact or from personal items that have touched the infected skin.
To kill all of the bacteria, hands must be washed thoroughly using soap and water or an alcohol-based hand sanitizer. People in hospitals, health care facilities, and nursing homes who have weak immune systems are at risk of more serious complications if they get HA-MRSA.
Some chemotherapy drugs and medicines taken after an organ transplant can weaken the immune system. So can having the human immunodeficiency virus HIV. Daycare centers, dormitories, jails, locker rooms, military barracks, prisons, and schools are common locations for the CA-MRSA.
MRSA outbreaks have also occurred among members of sports teams. This is because skin-to-skin contact as well as minor cuts and scrapes occur frequently. Several tests can show if you have MRSA.
Your doctor may take a sample from your wound or nasal passages. He or she may also take a sample of urine or blood to send to the laboratory. Results of this type of test called a culture should be ready in about 24 to 48 hours. It can take about 48 hours for the bacteria to grow. A newer rapid blood test provides results more quickly, in about 2 hours.
In serious cases, some strains of MRSA respond to antibiotics. Contact your doctor if you do not improve after a few days or if the infection gets worse.
For mild cases of MRSA, your doctor may drain the skin boil or abscess and cover the wound with a clean dressing or bandage. The dressing will need to be changed regularly. Your doctor may also prescribe an ointment to apply to the area.
The reason that hospitals seem to be hotbeds for resistant MRSA is because so many different strains are being thrown together with so many doses of antibiotics, vastly accelerating this natural selection process. It is a fact of life in the NHS that patients are at higher than normal risk of picking up a Staph infection on the wards.
This is for two reasons - firstly, that the population in hospitals tends to be older, sicker and weaker than the general population, making them more vulnerable to the infection.
Secondly, conditions in hospitals, which involve a great many people living cheek by jowl, examined by doctors and nurses who have just touched other patients, are the perfect environment for the transmission of all manner of infections. Staph infections can be dangerous in weakened patients, particularly if they can't be cleared up quickly with antibiotic treatments.
MRSA infections can prove tough to treat because they are resistant to treatment, making them more dangerous than a simple case of Staph. The number of reports of MRSA infections rises year by year - and the latest evidence suggests that deaths due to MRSA are increasing at a similar rate. VRSA, or vancomycin resistant Staphylococcus Aureus, has acquired resistance to a drug considered the "last line of defence" when all other antibiotics have failed.
Although new antibiotics are being developed all the time, pessimistic experts believe it is only a matter of time at current rates until virtually every weapon in the pharmaceutical arsenal is nullified. Nihilists suggest that there could come a point at which bacteria retake the upper hand, and doctors, as in previous centuries, have no answer to some bacterial infections.
It should be noted, they say, that humans have only had the upper hand over bacteria for a handful of decades - we have no right to expect that situation to last forever. The government is already trying to at least slow down the apparently relentless march of the bacteria.
At-risk populations include groups such as high school wrestlers, child care workers and people who live in crowded conditions. MRSA infections start out as small red bumps that can quickly turn into deep, painful abscesses. Staph skin infections, including MRSA , generally start as swollen, painful red bumps that might look like pimples or spider bites.
The affected area might be:. These red bumps can quickly turn into deep, painful boils abscesses that require surgical draining. Sometimes the bacteria remain confined to the skin. But they can also burrow deep into the body, causing potentially life-threatening infections in bones, joints, surgical wounds, the bloodstream, heart valves and lungs.
Keep an eye on minor skin problems — pimples, insect bites, cuts and scrapes — especially in children. If wounds appear infected or are accompanied by a fever, see your doctor. Different varieties of Staphylococcus aureus bacteria, commonly called "staph," exist.
Staph bacteria are normally found on the skin or in the nose of about one-third of the population. The bacteria are generally harmless unless they enter the body through a cut or other wound, and even then they usually cause only minor skin problems in healthy people. Predominance of methicillin-resistant Staphylococcus aureus among pathogens causing skin and soft tissue infections in a large urban jail: risk factors and recurrence rates.
Hota, B. Community-associated methicillin-resistant Staphylococcus aureus skin and soft tissue infections at a public hospital: do public housing and incarceration amplify transmission? Klein, E. Trends in methicillin-resistant Staphylococcus aureus hospitalizations in the United States, — One of the largest and most up-to-date cross-sectional studies on the burden of MRSA infections in US hospitals is presented.
Kallen, A. Health care-associated invasive MRSA infections, — JAMA , — Landrum, M. Epidemiology of Staphylococcus aureus blood and skin and soft tissue infections in the US military health system, — JAMA , 50—59 The changing epidemiology of bacteraemias in Europe: trends from the European Antimicrobial Resistance Surveillance System. Sutter, D. Changing susceptibility of Staphylococcus aureus in a US pediatric population.
Pediatrics , e This up-to-date cross-sectional study confirms a reduction in the MRSA incidence among the US paediatric population, mirroring adult trends. Community-associated methicillin-resistant Staphylococcus aureus : epidemiology and clinical consequences of an emerging epidemic.
Popovich, K. Genomic and epidemiological evidence for community origins of hospital-onset methicillin-resistant Staphylococcus aureus bloodstream infections. DeLeo, F. Methicillin-resistant Staphylococcus aureus strain USA origin and epidemiology. Centers for Disease Control and Prevention. Methicillin-resistant Staphylococcus aureus skin or soft tissue infections in a state prison—Mississippi, Wkly Rep.
Google Scholar. Hageman, J. Severe community-acquired pneumonia due to Staphylococcus aureus , — influenza season. Toleman, M. Systematic surveillance detects multiple silent introductions and household transmission of methicillin-resistant Staphylococcus aureus USA in the East of England. Glaser, P. Demography and intercontinental spread of the USA community-acquired methicillin-resistant Staphylococcus aureus lineage.
Murchan, S. Emergence, spread, and characterization of phage variants of epidemic methicillin-resistant Staphylococcus aureus 16 in England and Wales. Identification and characterization of phage variants of a strain of epidemic methicillin-resistant Staphylococcus aureus EMRSA Knight, G.
The tendency of dominant MRSA strains to shift over time is well documented in this paper. Johnson, A. Methicillin-resistant Staphylococcus aureus: the European landscape. Song, J. Arias, C. A prospective cohort multicenter study of molecular epidemiology and phylogenomics of Staphylococcus aureus bacteremia in nine Latin American countries.
Blomfeldt, A. Population-based epidemiology of Staphylococcus aureus bloodstream infection: clonal complex 30 genotype is associated with mortality. Rolo, J. High genetic diversity among community-associated Staphylococcus aureus in Europe: results from a multicenter study. Xie, X. Molecular epidemiology and characteristic of virulence gene of community-acquired and hospital-acquired methicillin-resistant Staphylococcus aureus isolates in Sun Yat-sen Memorial hospital, Guangzhou, Southern China.
BMC Infect. Otter, J. Molecular epidemiology of community-associated meticillin-resistant Staphylococcus aureus in Europe. Lancet Infect. Chuang, Y. Molecular epidemiology of community-associated meticillin-resistant Staphylococcus aureus in Asia. This paper presents one of a series of molecular epidemiologic studies that has markedly expanded our understanding of MRSA genetic diversity in Asia, collectively demonstrating generally greater genetic diversity than is seen in the United States.
Liu, Y. Molecular evidence for spread of two major methicillin-resistant Staphylococcus aureus clones with a unique geographic distribution in Chinese hospitals. Zhao, C. Harch, S. Health Perspect. Witte, W. Smith, T. Sung, J. Staphylococcus aureus host specificity: comparative genomics of human versus animal isolates by multi-strain microarray.
Microbiology , — Alam, M. Diep, B. Complete genome sequence of USA, an epidemic clone of community-acquired meticillin-resistant Staphylococcus aureus. Lancet , — Comparative analysis of virulence and toxin expression of global community-associated methicillin-resistant Staphylococcus aureus strains.
Holden, M. A genomic portrait of the emergence, evolution, and global spread of a methicillin-resistant Staphylococcus aureus pandemic. Genome Res. Gorwitz, R. Changes in the prevalence of nasal colonization with Staphylococcus aureus in the United States, — Lekkerkerk, W. Lucet, J. Prevalence and risk factors for carriage of methicillin-resistant Staphylococcus aureus at admission to the intensive care unit: results of a multicenter study. Shet, A. Colonization and subsequent skin and soft tissue infection due to methicillin-resistant Staphylococcus aureus in a cohort of otherwise healthy adults infected with HIV type 1.
Schechter-Perkins, E. Prevalence and predictors of nasal and extranasal staphylococcal colonization in patients presenting to the emergency department. Karanika, S. Colonization with methicillin-resistant Staphylococcus aureus and risk for infection among asymptomatic athletes: a systematic review and metaanalysis. Cluzet, V. Duration of colonization and determinants of earlier clearance of colonization with methicillin-resistant Staphylococcus aureus.
Mollema, F. Transmission of methicillin-resistant Staphylococcus aureus to household contacts. Huang, S. Strain-relatedness of methicillin-resistant Staphylococcus aureus isolates recovered from patients with repeated infection. This study shows that MRSA infection following either initial colonization or prior infection is most often caused by the same strain.
Calderwood, M. Staphylococcal enterotoxin P predicts bacteremia in hospitalized patients colonized with methicillin-resistant Staphylococcus aureus. Patel, A. Reversion of methicillin-resistant Staphylococcus aureus skin infections to methicillin-susceptible isolates. JAMA Dermatol. Iwase, T. Staphylococcus epidermidis Esp inhibits Staphylococcus aureus biofilm formation and nasal colonization.
Nature , — Matheson, A. Nasal swab screening for methicillin-resistant Staphylococcus aureus — how well does it perform? A cross-sectional study. Kelley, P. Blanc, D. High proportion of wrongly identified methicillin-resistant Staphylococcus aureus carriers by use of a rapid commercial PCR assay due to presence of staphylococcal cassette chromosome element lacking the mecA gene.
Warnke, P. Nasal screening for MRSA: different swabs—different results! Shaw, A. Detection of methicillin-resistant and methicillin-susceptible Staphylococcus aureus colonization of healthy military personnel by traditional culture, PCR, and mass spectrometry. Currie, A. Sensitivities of nasal and rectal swabs for detection of methicillin-resistant Staphylococcus aureus colonization in an active surveillance program.
Batra, R. Throat and rectal swabs may have an important role in MRSA screening of critically ill patients. Intensive Care Med. Gagnaire, J. Epidemiology and clinical relevance of Staphylococcus aureus intestinal carriage: a systematic review and meta-analysis. Expert Rev. Anti Infect. Mermel, L. Methicillin-resistant Staphylococcus aureus colonization at different body sites: a prospective, quantitative analysis.
Lauderdale, T. Carriage rates of methicillin-resistant Staphylococcus aureus MRSA depend on anatomic location, the number of sites cultured, culture methods, and the distribution of clonotypes. McKinnell, J. Quantifying the impact of extranasal testing of body sites for methicillin-resistant Staphylococcus aureus colonization at the time of hospital or intensive care unit admission. Anatomic sites of colonization with community-associated methicillin-resistant Staphylococcus aureus.
Vos, M. Bartels, M. Rise and subsequent decline of community-associated methicillin resistant Staphylococcus aureus STIVc in Copenhagen, Denmark through an effective search and destroy policy. Jain, R. Veterans Affairs initiative to prevent methicillin-resistant Staphylococcus aureus infections.
This study demonstrates that the implementation of a MRSA bundle that couples active surveillance with contact precautions and hand hygiene results in decreased rates of health-care-associated MRSA infections. Robicsek, A. Topical therapy for methicillin-resistant Staphylococcus aureus colonization: impact on infection risk. Harbarth, S. Universal screening for methicillin-resistant Staphylococcus aureus at hospital admission and nosocomial infection in surgical patients.
Saraswat, M. Preoperative Staphylococcus aureus screening and targeted decolonization in cardiac surgery. Jog, S. Impact of preoperative screening for meticillin-resistant Staphylococcus aureus by real-time polymerase chain reaction in patients undergoing cardiac surgery.
Targeted versus universal decolonization to prevent ICU infection. This large multicentre study shows that universal decolonization is more effective than targeted decolonization or screening and isolation in reducing rates of MRSA clinical isolates and bloodstream infection in patients in the ICU. Climo, M. Effect of daily chlorhexidine bathing on hospital-acquired infection. This study shows that daily bathing with chlorhexidine reduces the risks of acquisition of multidrug-resistant organisms and hospital-acquired bloodstream infections.
Lindgren, A. Eradication of methicillin-resistant Staphylococcus aureus MRSA throat carriage: a randomised trial comparing topical treatment with rifampicin-based systemic therapy. Agents 51 , — Kaasch, A. Use of a simple criteria set for guiding echocardiography in nosocomial Staphylococcus aureus bacteremia. Clinical practice guidelines for the diagnosis and management of intravascular catheter-related infection: Update by the Infectious Diseases Society of America.
Neely, M. Are vancomycin trough concentrations adequate for optimal dosing? The clinical significance of vancomycin minimum inhibitory concentration in Staphylococcus aureus infections: a systematic review and meta-analysis.
Fowler, V. Daptomycin versus standard therapy for bacteremia and endocarditis caused by Staphylococcus aureus.
This is one of very few RCTs addressing the treatment of MRSA bacteraemia or endocarditis, proving daptomycin is non-inferior to vancomycin. Silverman, J. Inhibition of daptomycin by pulmonary surfactant: in vitro modeling and clinical impact. Sharma, M. High rate of decreasing daptomycin susceptibility during the treatment of persistent Staphylococcus aureus bacteremia.
Gasch, O. Emergence of resistance to daptomycin in a cohort of patients with methicillin-resistant Staphylococcus aureus persistent bacteraemia treated with daptomycin.
Stryjewski, M. Raad, I. Efficacy and safety of weekly dalbavancin therapy for catheter-related bloodstream infection caused by gram-positive pathogens. Wilcox, M. Complicated skin and skin-structure infections and catheter-related bloodstream infections: noninferiority of linezolid in a phase 3 study. Casapao, A. Large retrospective evaluation of the effectiveness and safety of ceftaroline fosamil therapy.
Davis, J. Combination of vancomycin and beta-lactam therapy for methicillin-resistant Staphylococcus aureus bacteremia: a pilot multicenter randomized controlled trial. US National Library of Medicine. Thwaites, G. Adjunctive rifampicin for Staphylococcus aureus bacteraemia ARREST : a multicentre, randomised, double-blind, placebo-controlled trial.
Cosgrove, S. Clinical Infectious Diseases ; Rehm, S. Daptomycin versus vancomycin plus gentamicin for treatment of bacteraemia and endocarditis due to Staphylococcus aureus : subset analysis of patients infected with methicillin-resistant isolates.
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